Adverse Effects Brought on by High Doses of CBD
Let’s start with the apparent potential offender. Most people assume that for instance if two drops are helping them improve pain management by 20% each week, then increasing the dose to ten drops should enhance their recovery by 100%. However, because there is a lack of clinical evidence in this regard favouring CBD oil or against it, we have to look at an FDA approved CBD drug called Epidiolex. The drug is used to treat childhood epilepsy.
Clinical trials of Epidiolex on children between the ages of 2 and 18, prescribed high doses of regular CBD administration for up to 14 weeks will be referenced in this section. Daily doses administered are equivalent to 1,360 mg per 150-pound adult. For reference, this is around the entire standard bottle of CBD oil.
The adverse effects noted during these clinical trials were:
- Chronic tiredness
- Gastrointestinal issues
- Lower appetite
- Alteration of liver enzymes
The side effects became apparent during the first week as the doses were being ramped up. However, the symptoms were shown to subside once the dosage stabilized. Lowering doses was also shown to be an effective way to help decrease instances of side effects. So, anyone who is experiencing adverse effects with the use of CBD oil might want to wait it out for up to a week, try lowering their doses, switch to a better or different product.